Yu Du Selected Research

Hypoxia (Hypoxemia)

1/2022	Rational Design for Nitroreductase (NTR)-Responsive Proteolysis Targeting Chimeras (PROTACs) Selectively Targeting Tumor Tissues.
1/2022	Hypoxia-induced ebv-circLMP2A promotes angiogenesis in EBV-associated gastric carcinoma through the KHSRP/VHL/HIF1α/VEGFA pathway.
9/2021	NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway.
1/2020	TREM-2-p38 MAPK signaling regulates neuroinflammation during chronic cerebral hypoperfusion combined with diabetes mellitus.
1/2020	Leptin Receptor Deficiency Protects Mice against Chronic Cerebral Hypoperfusion-Induced Neuroinflammation and White Matter Lesions.
1/2019	Long non-coding RNA MALAT1 mediates hypoxia-induced pro-survival autophagy of endometrial stromal cells in endometriosis.
11/2018	Autophagy contributes to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis.
1/2018	Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.
1/2017	Estrogen stabilizes hypoxia-inducible factor 1α through G protein-coupled estrogen receptor 1 in eutopic endometrium of endometriosis.
1/2017	Hypoxia-inducible factor-1α promotes endometrial stromal cells migration and invasion by upregulating autophagy in endometriosis.

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Yu Du Research Topics

Disease

37	Neoplasms (Cancer) 11/2022 - 03/2012
11	Hypoxia (Hypoxemia) 01/2022 - 01/2016
11	Cataract (Cataracts) 10/2021 - 07/2017
10	Atherosclerosis 01/2022 - 06/2012
8	Cardiovascular Diseases (Cardiovascular Disease) 03/2022 - 01/2015
8	Inflammation (Inflammations) 01/2022 - 01/2018
8	Endometriosis 10/2020 - 03/2016
8	Infections 01/2020 - 12/2014
7	Breast Neoplasms (Breast Cancer) 01/2022 - 01/2018
6	Pain (Aches) 07/2021 - 04/2013
6	Coronary Artery Disease (Coronary Atherosclerosis) 03/2020 - 08/2017
5	Carcinoma (Carcinomatosis) 01/2022 - 01/2017
5	Insulin Resistance 01/2022 - 02/2015
5	Ischemia 12/2021 - 09/2012
5	Poisoning 01/2021 - 11/2009
5	Wounds and Injuries (Trauma) 01/2021 - 01/2004
5	Squamous Cell Carcinoma of Head and Neck 05/2015 - 01/2014
4	Lung Neoplasms (Lung Cancer) 01/2022 - 05/2015
4	Neoplasm Metastasis (Metastasis) 01/2022 - 02/2016
4	Carcinogenesis 01/2022 - 01/2018
4	Heart Failure 11/2021 - 07/2014
3	COVID-19 06/2022 - 11/2020
3	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 07/2014
3	Neuroinflammatory Diseases 09/2021 - 12/2019
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 02/2021 - 10/2018
3	Hypokalemia 01/2021 - 05/2018
3	Obesity 01/2021 - 06/2016
3	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2020 - 01/2020
3	Pathologic Constriction (Stenosis) 01/2020 - 06/2016
3	ST Elevation Myocardial Infarction 10/2019 - 10/2019
3	Lymphoma (Lymphomas) 01/2019 - 09/2013
3	Hemorrhage 11/2018 - 06/2017
3	Head and Neck Neoplasms (Head and Neck Cancer) 04/2014 - 07/2013
2	Nervous System Diseases (Neurological Disorders) 03/2022 - 01/2022
2	Reperfusion Injury 12/2021 - 10/2019
2	Neuroblastoma 11/2021 - 01/2018
2	Cognitive Dysfunction 09/2021 - 01/2020
2	Lupus Nephritis 02/2021 - 12/2020
2	Type 2 Diabetes Mellitus (MODY) 01/2021 - 04/2018
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2021 - 01/2021
2	Stomach Neoplasms (Stomach Cancer) 10/2020 - 01/2020
2	Shock 10/2020 - 01/2018
2	Hepatocellular Carcinoma (Hepatoma) 01/2020 - 04/2013

Drug/Important Bio-Agent (IBA)

19	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2012
15	Biomarkers (Surrogate Marker)IBA 01/2022 - 07/2013
14	Pharmaceutical PreparationsIBA 01/2022 - 05/2010
9	Messenger RNA (mRNA)IBA 01/2022 - 01/2015
7	Glucose (Dextrose)FDA LinkGeneric 02/2020 - 02/2015
5	Therapeutic UsesIBA 12/2022 - 09/2019
5	Circular RNAIBA 01/2022 - 10/2020
5	LipidsIBA 05/2021 - 12/2009
5	CholesterolIBA 04/2020 - 12/2009
4	MicroRNAs (MicroRNA)IBA 11/2022 - 01/2015
4	Indicators and Reagents (Reagents)IBA 05/2022 - 01/2017
4	AdipokinesIBA 01/2022 - 06/2016
4	CytokinesIBA 01/2022 - 01/2018
4	Biological ProductsIBA 01/2022 - 02/2003
4	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 02/2003
4	Estrogens (Estrogen)FDA Link 01/2021 - 01/2017
4	WD repeat containing planar cell polarity effectorIBA 03/2020 - 10/2017
4	Analgesics (Analgesic Drugs)IBA 11/2019 - 04/2013
4	Caspase 3 (Caspase-3)IBA 01/2019 - 01/2004
3	ErbB Receptors (EGF Receptor)IBA 01/2022 - 04/2014
3	Interleukin-6 (Interleukin 6)IBA 12/2021 - 11/2020
3	AntioxidantsIBA 09/2021 - 10/2018
3	AcidsIBA 01/2021 - 01/2020
3	CateninsIBA 12/2019 - 04/2013
3	Long Noncoding RNAIBA 08/2019 - 01/2019
3	Insulin (Novolin)FDA Link 01/2018 - 02/2015
3	salicylhydroxamic acid (SHAM)IBA 05/2013 - 09/2012
2	Epidermal Growth Factor (EGF)IBA 01/2022 - 04/2014
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 01/2021
2	Proteolysis Targeting ChimeraIBA 01/2022 - 01/2022
2	Antiviral Agents (Antivirals)IBA 12/2021 - 07/2020
2	Peroxynitrous Acid (Peroxynitrite)IBA 12/2021 - 01/2020
2	vanadium pentoxideIBA 11/2021 - 10/2013
2	AntigensIBA 08/2021 - 01/2011
2	thiamine triphosphorate (TTP)IBA 07/2021 - 01/2018
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2021 - 10/2020
2	arsenic disulfide (realgar)IBA 01/2021 - 01/2021
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2021 - 01/2020
2	Crystallins (Crystallin)IBA 01/2021 - 01/2018
2	Choline (Choline Chloride)IBA 01/2021 - 01/2021
2	trimethyloxamine (trimethylamine N-oxide)IBA 01/2021 - 01/2021
2	Adenosine Triphosphate (ATP)IBA 01/2021 - 09/2018
2	Phosphotransferases (Kinase)IBA 10/2020 - 01/2019
2	Anti-Bacterial Agents (Antibiotics)IBA 10/2020 - 12/2014
2	EnzymesIBA 05/2020 - 11/2018
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2020 - 11/2018
2	HexokinaseIBA 01/2020 - 11/2018
2	Phenobarbital (Luminal)FDA Link 01/2020 - 04/2018
2	Matrix Metalloproteinases (MMPs)IBA 01/2020 - 10/2017

Therapy/Procedure

21	Therapeutics 04/2022 - 12/2012
4	Radiotherapy 01/2021 - 09/2013
4	Slit Lamp 01/2020 - 06/2017
4	Percutaneous Coronary Intervention 10/2019 - 04/2018
3	Intraocular Lenses (Intraocular Lens) 01/2020 - 10/2019
2	Drug Therapy (Chemotherapy) 01/2021 - 09/2013
2	Immunotherapy 01/2021 - 01/2019
2	Diskectomy (Discectomy) 01/2020 - 12/2019